NMR Suite Archives

Chenomx NMR Suite V10 includes:

PROCESSOR:
- Addition of Fumarate and Maleate as Internal Standards.
- Reusable baseline breakpoints locations

PROFILER

• Re-introduction of Legacy Autofit (from Version 8.6 and earlier)
• Introduction of COMPLETE Autofit: an all-new Automatic Iterative Profiler that performs numerous, parallel approaches to a complete autofit of your NMR spectra, then identifies the lowest statistical errors and provides a recommended ‘BEST’ fit.
• Improved automatic positioning of compound peak clusters
• Batch Export of Spectral Data in binary and TXT format
• Batch Export in JCAMP format
  • Enhanced drag-n-drop support through-out the entire suite
  • Complete native support for the Apple M1 chip
  • Enhanced Preferences settings [“Default Compound Sets” and “Concentration Fitting” are new and allow for better control of the software]

Download V10 for 64bit Windows

Download V10 for 64bit macOS

Download V10 for 64bit macOS M1

Download V10 for 64bit Linux

Version 9 of Chenomx NMR Suite includes:

• Enhanced drag-n-drop support through-out the entire suite
• Complete native support for the Apple M1 chip
• Enhanced Preferences settings [“Default Compound Sets” and “Concentration Fitting” are new and allow for better control of the software]


PROCESSOR

• Improved Automatic Phasing
• Batch Import of Sample pH Information from XLS workbooks

PROFILER

• Improved Automatic Concentration Fitting for both batched and individual spectra.
• Export of Statistical Standard Deviation errors for building Confidence Indices
• Much improved MetaProfile Importing (allows for the selection of specific compounds) as well as Batch Profile Importing.
• Improved Compound Searching within Spectral Regions

Download V9 for 64bit Windows

Download V9 for 64bit macOS

Download V9 for 64bit macOS M1

Download V9 for 64bit Linux

Version 8.6 of Chenomx NMR Suite adds new tools to the Profiler, Processor, Compound Builder and Spin Simulator as well as bug fixes:

Processor

• Improved automatic phasing.
• New automatic baseline algorithm.
• New Selector Box selects several baseline breakpoints at once.
• New peak reference tool brings up interface to specify desired frequency and automatically modifies cluster transforms.

Profiler

• New Compound Snapper tool gets best cluster fit location.
• New pH tool optimizes fit position of pH sensitive clusters.
• New Batch Import Profile tool from source CNX to several other CNX files.
• New Overlay Sum Line and Overlay Subtraction Line.
• Improved Sequential Autofit.

Compound Builder

• New Overlay Subtraction Line

Spin Simulator

• Support for Negative Coupling Constants.

Download Complete V8.6 Release Notes

Download V8.6 for 64bit Windows
Download V8.6 for 64bit macOS
Download V8.6 for 64bit Linux

Version 8.5 of Chenomx NMR Suite updates and enhances the compound libraries. This includes:

• Improved and re-calibrated entries 700 MHz Reference Library (121 updated compounds).
• Improved multi pH data in 35 compounds in the 500, 600, and 800 MHz Reference Libraries.
• Introduced C13 labelled compound library entries available on request and for contract service analysis.

This update also supports the latest version of Java 11.numerous small issues.

Download for 64bit Windows
Download for 64bit macOS
Download for 64bit Linux

New Reporting Software from Chenomx » We are pleased to announce the release of DiscoverM, software for statistical analysis and reporting of data for Chenomx NMR Suite data. This software has been developed together with researchers at the University of Alberta and is available at no extra charge. Chenomx users who are licensed to use Chenomx NMR Suite version 8.4. will be able to export spectral results from project files to DiscoverM.  Please refer to https://www.chenomx.com/products/discoverm/ for more detail.

New Export to DiscoverM Feature » We've added an Export to DiscoverM feature to Profiler. This feature will export concentrations from a group of files in Profiler to be used in our new statistical analysis and reporting software, DiscoverM.

Improved Bruker Processing » We've improved our processing of Bruker FIDs to significantly reduce "smile" effects at the edges of the processed spectrum.

Improved All User Licensing » We've simplified the process of licensing Chenomx NMR Suite for all users of a computer on macOS and Linux.

Numerous Updates and Fixes » We've updated our Java environment to the latest version of Java 9 and fixed numerous small issues.

Download for Windows
Download for Mac

Numerous Updates and Fixes » We've updated our Java environment to the latest version of Java 8 and fixed a number of small issues in Processor and Profiler.

New Automatic Baseline Correction » We've added a new Whittaker Spline automatic baseline correction method in Processor and redesigned the Baseline Correction user interface.

Improved File Format Support » We've fixed some issues with JCAMP compatibility and improved support for MNOVA and NMRPipe files. We've also enhanced our support for working with newer Bruker fids.

Windows 10 / 8 / 7 / Vista (32-bit)
Windows 10 / 8 / 7 / Vista (64-bit)
Mac OS X 10.13 - 10.8.3 (64-bit)
Linux x86 (32-bit)
Linux x86 (64-bit)

New Simulated Reference Compounds » 7 new compound libraries have been simulated and are now available in our Reference Library! They are available on the following Add Compounds Wizard page in Library Manager.

Numerous Updates and Fixes » We've updated our Java environment to the latest version of Java 8 and fixed a number of small issues in Processor and Profiler.

New Pivot Point Phasing » We've added Pivot Point functionality to our Phase Correction tool in Processor. Once you have corrected a peak shape with the Zero-order Phase slider you can turn on the Use Pivot Point checkbox and position the new line on the graph to define your pivot point. While you adjust the First-order Phase, Processor will then keep the phasing line shape correct at your pivot point by automatically adjusting the corresponding Zero-order Phase.

Improved Generate Cluster for Region and Optimize Peak Shapes » We've improved our automated cluster generation algorithm as well as our peak shape optimization routines. The generated clusters have more realistic peak shapes and composition.

Windows 10 / 8 / 7 / Vista (32-bit)
Windows 10 / 8 / 7 / Vista (64-bit)
Mac OS X 10.10 - 10.8.3 (64-bit)
Linux x86 (32-bit)
Linux x86 (64-bit)

Improved Region-Based Fitting » You can now create compounds that use a simpler, region-based fitting style. This new fitting mode relies on an estimated lineshape and does not require compounds to have a known sample concentration. It is ideal for quickly modelling the unknown compounds in your mixture samples. Profiler will report the spectral area of these new compounds rather than an exact concentration allowing you to easily analyse and compare the significance of unknown regions in your NMR studies.

Export Vector Formats » Our "Export Spectrum Image..." feature now supports resolution independant vector graphic file formats. The following vector formats are available:

• Scalable Vector Graphic (.svg)
• Portable Document Format (.pdf)
• Encapsulated PostScript (.eps)

New Preserve Options in the Files Panel » The Files panel available in most of our modules allows quick access to a group of files in a single folder. We have added a drop down menu that allows you to configure some of the actions taken when opening files through this panel.

Hardware Acceleration Preference » It is now possible to disable hardware accelerated graphics for the entire application in the General section of Preferences. This should help with graphical issues some users have encountered on older hardware.

New Reference Compound Additions » The following new compounds were added at all frequencies to our Reference Library:

• 2,3,4-Trihydroxybenzoate
• 2,6-Dihydroxybenzoate
• 5-Aminopentanoate
• Desaminotyrosine
• Guanidinosuccinate
• Xylitol

More details can be found here.

Batch Export Improvement » Profiler's Batch Export wizard has a new page that will allow you to avoid exporting concentrations that have been set to zero. Zero value concentrations can be used in your profiling workflow while also ensuring that they do not have harmful effects on your data analysis.

Check / Uncheck All Overlays » The Legend panel in Profiler now offers the ability to toggle the visibility of all overlays at once. This feature can be found in a new drop down menu attached to the "Overlay Lines" category.

Excel Export Improvements » Excel formatting in Profiler's export feature has been improved. Columns will now appear automatically sized whenever possible and customs colors that are set for particular compounds will actually be used to style the data in that compound's cells.

New Batch Processing Wizard » A new Batch Processing wizard has been added to Processor. This wizard lets you perform processing steps on a group of .cnx files with a single operation.

Compound Set from Profile » Library Manager can now create a new compound set which will include all of the profiled compounds from a chosen CNX file.

Windows 10 / 8 / 7 / Vista (32-bit)
Windows 10 / 8 / 7 / Vista (64-bit)
Mac OS X 10.10 - 10.8.3 (64-bit)
Linux x86 (32-bit)
Linux x86 (64-bit)

Graph Grid Lines » You are now able to turn on and off grid lines on the spectrum graph. This new graph aid will help in situations where you are manually adjusting peak areas.

Spectrum Details Panel » We've made a new Spectrum Details Panel. You can see all the details about the spectrum you have loaded in this panel.

New Reference Compound Additions » New compounds added at all frequencies for this release include:

• 1,3-Diaminopropane
• 3,4-Dihydroxybenzeneacetate
• 4-Guanidinobutanoate
• Cellobiose
• Citraconate
• Erythritol
• Gallate
• Phenylglyoxylate
• Pyrocatechol
• D-Threitol
• Syringate

More details can be found here.

Brand New Look and Feel » Chenomx NMR Suite has a brand new look and feel. Not only do we have a new improved user interface, but we are now using the latest java technology! This new java technology utilizes the latest in hardware graphics acceleration and will allow us even more graphical options into the future. Test out the software today and notice the difference!

Improved Autofit » The autofit algorithm has been improved to now account for area already fit by other compounds in convoluted areas. Also, this new algorithm doesn't only rely on compound pH equations, but takes user input corrections as well. Give it a try!

Batch Fit and Batch Edit » Batch Fit and Batch Edit are two new tools redefined from the old Batch Profile tool. Batch Fit uses a new and improved algorithm to fit multiple metabolites across multiple files. This tool will help speed up your analysis time while profiling spectra. Batch Edit contains tools to modify or edit multiple spectra simultaneously. There is a new tutorial on how to use Batch Fit and review multiple spectra efficiently found with the software under the Help menu.

Improved Spin Definition UI » We've improved the overall layout, and the way you see and interact with spin definitions. We've made this change to be more consistent with Compound Builder.

Windows 8 / 7 / Vista (32-bit)
Windows 8 / 7 / Vista (64-bit)
Mac OS X 10.9 - 10.8.3 (64-bit)
Linux x86 (32-bit)
Linux x86 (64-bit)

Stack Plots for Overlays » You are now able to not only overlay multiple spectra in Chenomx Processor and Profiler, but you can also stack these spectra with an offset. Stack plots help you visualize the differences between spectra. Stacking is easily applied to overlaid spectra with a simple drag of the mouse.

New Reference Compound Additions » New compounds added at all frequencies for this release include:

• Lactulose
• 2-Furoylglycine
• Agmatine
• Chlorogenate
• Glucose-1-phospate
• Glucose-6-phosphate
• Hydroxyacetone
• IMP
• UMP

More details can be found here.

Updated Compounds and new 400 MHz Compound Additions » Compounds that were updated at 500 MHz to 800 MHz, and added at 400 MHz for this release include:

• Xylose
• Ornithine
• Histidine
• Phenylalanine
• Alanine
• Propylene glycol
• cis-Aconitate
• 3-Hydroxymandelate

More details can be found here.

Reference Card Editor » You can now create custom reference cards using the new Reference Card Editor. This tool will help you enter all of the necessary information needed in a reference card. Save these new reference cards (.xmc) and Chenomx NMR Suite will automatically load them for use in the Reference Card Panel along with your custom compounds.

Easier to add new Spin Definitions » We've improved the way you can add new spin definitions. You can now toggle on a mode where clicking on the graph will add a single nuclei spin definition with a resonance center at the frequency that you clicked.

Independent Spin Systems » Spin systems are now independent of each other in terms of overall intensity. This will allow you to model separate forms of the same compound that have different abundances in solution, in separate spin systems.

Windows 8 / 7 / Vista / XP (32-bit)
Windows 8 / 7 / Vista / XP (64-bit)
Mac OS X 10.9 - 10.7.3 (64-bit)
Linux x86 (32-bit)
Linux x86 (64-bit)