Chenomx offers a broad range of services for metabolomics researchers, including:

  • Sample Preparation » Chenomx has in-depth expertise in preparing samples for NMR experiments with a broad range of sample types. Sample types we have experience in working with include urine, blood (serum/plasma), CSF, saliva, and cell extracts.
  • NMR Data Acquisition » Chenomx uses state-of-the-art NMR equipment for its metabolomics work, ranging in field strength from 500 MHz to 800 MHz.
  • Metabolite Identification and Quantification » Chenomx has years of experience applying Chenomx NMR Suite to challenging and novel metabolomics experiments - leverage this expertise and have us identify and quantify metabolites in your NMR spectra.
  • Statistical Analysis » Chenomx can provide in-depth statistical analysis of data sets using PCA and PLS-DA.

Find out more about what's possible with Chenomx's metabolic profiling services by reading one of our case studies:

  • Analyzing Metabolic Effects of Acetaminophen. (PDF)
    Acetaminophen is the most common identifiable cause of acute liver failure, and is an excellent model compound for studying liver toxicity. Acetaminophen toxicity has thus become a very active area of research. Identifying and quantifying metabolites associated with acetaminophen toxicity is an integral part of this research, and Chenomx is uniquely equipped to extract this information from biofluid samples.
  • Developing Biomarkers for Adverse Response to Drugs or Chemicals. (PDF)
  • Drug-induced liver injury is the leading reason that drug candidates fail. Identifying a suite of toxicity biomarkers for use in preclinical screening of drug candidates will allow drugs with harmful side effects to be identified earlier. Biomarkers that can be used to monitor or stage diseases will also offer insight into the net metabolic effect of a drug and can provide information for developing new drugs or adjusting treatment. Chenomx software offers powerful tools to aid in identifying these biomarkers.

Find out more about applying Chenomx metabolic profiling services to specific sample types by reading our information sheets:

  • Chenomx MetaProfile for Serum. (PDF)
  • Chenomx MetaProfile for Cerebrospinal Fluid (CSF). (PDF)
  • Chenomx MetaProfile for Urine. (PDF)
  • Chenomx MetaProfile for Saliva. (PDF)
  • Chenomx MetaProfile for Cell Extracts. (PDF)

For more information on our metabolic profiling and data analysis services, download our brochure or contact us.