Product Overview

Chenomx NMR Suite

Take a tour of Chenomx NMR Suite.

Chenomx NMR suite is an integrated suite of tools that allow you to easily identify and quantify metabolites in NMR spectra. The following products make up Chenomx NMR Suite:

Chenomx Profiler

Take a tour of Chenomx Profiler.

Chenomx Profiler offers you a broad range of tools to assist in identifying and quantifying compound concentrations based on data in an NMR spectrum.

Using a compound library of over 260 unique spectral signatures together with sophisticated computer-assisted fitting routines, you can accomplish in minutes what would have taken hours or days using manual analysis methods.

Chenomx Compound Builder

Take a tour of Chenomx Signature Builder.

Chenomx Signature Builder was developed to address a recurring customer request: the capability to add custom compounds to a Compound Library. Signature builder allows a user to create a signature that models the compound of interest.

This capability lets users create signatures for compounds that are not present in the standard Chenomx Compound Library, and subsequently use those proprietary compounds in an analysis within Profiler.

Chenomx Spin Simulator

Take a tour of Chenomx Spin Simulator.

Chenomx Spin Simulator is a simple yet powerful tool for creating simulations of NMR spectra, based on user-defined spin systems, coupling relationships and reference spectra. You can use these simulations as starting points for creating your own compound signatures based on fundamentals of NMR theory.

 

Chenomx Library Manager

Take a tour of Chenomx Library Manager.

Chenomx Library Manager allows you to create and manage Compound Sets for use in Profiler. Compound Sets can contain any compound signatures in your library, including those from the Chenomx library as well as those that you create with Compound Builder.

You can tailor a Compound Set to a specific project. For example, in a research project, you may only be interested in examining the concentrations of five particular compounds for a drug study; you can use Library Manager to create a Compound Set including only those compoun

Chenomx Processor

Take a tour of Chenomx Processor.

Chenomx Processor allows a variety of native spectrum formats to be converted into the Chenomx file format. These include:

• Varian
• Bruker
• JCAMP (Version 5.0 and above)

In addition, Processor allows users to identify or manually override the automatically determined parameters for the Chemical Shift Indicator. Processor can also be used to determine and set a variety of properties for the spectrum, such as pH.

What's New

Chenomx NMR Suite

• Set Zoom Region » It is now possible to set the zoom region based on user-specified ranges (horizontal and vertical).
• Selected Region » The selected region can now be resized by grabbing and moving its edges.
• Internet-Enabled Reference Panel » The Reference Panel now automatically retrieves compound-specific information from the Internet, meaning the Reference Panel is always expanding and improving as we retrieve new information for individual compounds.
• Enhanced Cluster Navigator » You can set the view to encompass multiple clusters by clicking and dragging them in the Cluster Navigator.
  

Chenomx Profiler

• Improved Compound Interface » Compounds are now displayed as filled-in shapes that can be easily manipulated.
• Improved Compound Selection » Selecting a compound of interest in a heavily-overlapped region has been improved. Clicking the area under the sum line automatically cycles through the compounds that contribute to the sum area. Right-clicking the sum area will provide a context-sensitive menu that provides information on all compounds contributing to the signal in that region.
• Improved Export Spectrum Graphic » Exporting spectrum graphics is now an easy-to-use wizard.
• Improved Spectral Binning » Spectral binning is now easier than ever with the new spectral binning wizard.
• Compound Versioning » Identifying and reconciling out-of-date compounds is now possible with Profiler's new compound versioning support.
• Compound Coloring » Assign custom colors to compounds, and pin them to the Spectrum View with Profiler's Custom Color and Highlight annotations.
• Compound "Starring" » Note important compounds using Profiler's "starring" tool.
• Smaller and Faster Spectrum Files » Previous versions of Chenomx NMR Suite "embedded" a copy of the compound library in each spectrum file (.cnx). Chenomx NMR Suite 5.0 makes spectrum files smaller and faster to load by only storing references to a compound in the spectrum file itself; the compound is then loaded on demand when the file is opened in Profiler.
  

Chenomx Compound Builder

• Compound Builder » Compound Builder is a new module that inherited the free-form and automated Lorentzian fitting tools from Signature Builder.

Chenomx Spin Simulator

• Spin Simulator » Spin Simulator is a new module that inherited the theoretical basis of creating compound signatures from Signature Builder. The simple first-order simulation performed by Signature Builder has been replaced with full quantum mechanical spin simulation, which models higher-order effects using spin definitions and spin-spin coupling, allowing more accurate simulations. Spin Simulator can export simulations to Compound Builder for "fine-tuning" before they are used in Profiler.
  

Chenomx Library Manager

• Library Manager » Library Manager has been redesigned from the ground up to make compound and compound list management as intuitive and as powerful as possible. Creating "Compound Sets" that contain a set of compounds specific to a sample type or study is a simple drag-and-drop. "Smart Compound Sets" can be created to automatically filter the compound library to a set of compounds that match specified criteria.
• New Compound Library Format » The compound library format used by Chenomx NMR Suite has been completely redesigned. The compound library is now simply a folder made up of one or more Chenomx Compound files (.xcpd). Adding or removing compounds from your compound library is as simple as adding or removing compounds from the library folder.
  

Chenomx Processor

• DFTMP » DFTMP has been added to Processor's list of supported pH indicators.